Michael J Ausserlechner Selected Research

3- cyclopropylmethyl- 7- phenyl- 3H- pyrrolo(3,2- f)quinolin- 9(6H)- one

5/2017

The tubulin inhibitor MG-2477 induces autophagy-regulated cell death, ROS accumulation and activation of FOXO3 in neuroblastoma.

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Michael J Ausserlechner Research Topics

Disease

15	Neoplasms (Cancer) 12/2022 - 07/2008
11	Neuroblastoma 12/2022 - 03/2010
3	Neoplasm Metastasis (Metastasis) 12/2022 - 06/2012
3	Leukemia 01/2014 - 11/2009
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 07/2013 - 11/2009
1	Chronic Pain 01/2022
1	Ovarian Neoplasms (Ovarian Cancer) 01/2022
1	Colonic Neoplasms (Colon Cancer) 01/2021
1	Trifunctional Protein Deficiency With Myopathy And Neuropathy 01/2021
1	Wounds and Injuries (Trauma) 10/2019
1	Hyperglycemia 01/2019
1	VLCAD deficiency 01/2018
1	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 01/2018
1	Muscle Weakness 01/2018
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2018
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 07/2013
1	T-Cell Leukemia (Leukemia, T Cell) 11/2009
1	Osteosarcoma (Osteogenic Sarcoma) 07/2008
1	Autosomal Recessive Polycystic Kidney (Polycystic Kidney Disease, Infantile, Type I) 05/2006

Drug/Important Bio-Agent (IBA)

6	Pharmaceutical PreparationsIBA 12/2022 - 01/2014
3	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 01/2018
3	Transcription Factors (Transcription Factor)IBA 01/2020 - 09/2014
3	Proteins (Proteins, Gene)FDA Link 01/2019 - 08/2013
3	Apoptosis Regulatory ProteinsIBA 01/2014 - 03/2010
2	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2019 - 09/2014
2	CaspasesIBA 01/2019 - 01/2014
2	SurvivinIBA 01/2019 - 03/2016
2	X-Linked Inhibitor of Apoptosis ProteinIBA 01/2014 - 01/2014
2	Caspase 8 (Caspase-8)IBA 01/2014 - 06/2012
1	Opioid Analgesics (Opioids)IBA 01/2022
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022
1	Methadone (Dolophine)FDA LinkGeneric 01/2022
1	mu Opioid Receptors (mu Opioid Receptor)IBA 01/2022
1	Analgesics (Analgesic Drugs)IBA 01/2022
1	SphingomyelinsIBA 01/2021
1	CeramidesIBA 01/2021
1	Deoxyglucose (2 Deoxy D glucose)IBA 01/2021
1	CarbenoxoloneIBA 01/2020
1	repaglinide (Prandin)FDA Link 12/2019
1	LumicanIBA 12/2019
1	OxalatesIBA 12/2019
1	SaltsIBA 12/2019
1	CalciumIBA 10/2019
1	Mitochondrial Trifunctional ProteinIBA 01/2018
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2018
1	Tubulin ModulatorsIBA 05/2017
1	3- cyclopropylmethyl- 7- phenyl- 3H- pyrrolo(3,2- f)quinolin- 9(6H)- oneIBA 05/2017
1	DNA (Deoxyribonucleic Acid)IBA 11/2016
1	Caspase 9IBA 01/2014
1	Inhibitor of Apoptosis ProteinsIBA 01/2014
1	Etoposide (VP 16)FDA LinkGeneric 01/2014
1	Prednisone (Sone)FDA LinkGeneric 07/2013
1	Forkhead Box Protein O3IBA 07/2013
1	Decitabine FDA Link 06/2012
1	LigandsIBA 06/2012
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2012
1	Bortezomib (Velcade)FDA Link 03/2010
1	Proteasome InhibitorsIBA 03/2010
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 11/2009
1	Proto-Oncogene Proteins c-bcl-2 (Proto Oncogene Proteins c bcl 2)IBA 11/2009
1	Cyclin-Dependent Kinase Inhibitor p16IBA 11/2009
1	Small Interfering RNA (siRNA)IBA 11/2009
1	GlucocorticoidsIBA 11/2009
1	Pyruvate KinaseIBA 07/2008
1	PhosphoenolpyruvateIBA 07/2008
1	IsoenzymesIBA 07/2008
1	Peptide AptamersIBA 07/2008

Therapy/Procedure

9	Therapeutics 01/2020 - 06/2012
1	Precision Medicine 12/2022
1	Drug Therapy (Chemotherapy) 01/2019
1	Transplantation 05/2006
1	Nephrectomy 05/2006